Context dependent effects of ventral tegmental area inactivation on spatial working memory
نویسندگان
چکیده
منابع مشابه
Effects of prefrontal cortical inactivation on neural activity in the ventral tegmental area.
Dopamine (DA) cells have been suggested to signal discrepancies between expected and actual rewards in reinforcement learning. DA cells in the ventral tegmental area (VTA) receive direct projections from the medial prefrontal cortex (mPFC), a structure known to be one of the brain areas that represents expected future rewards. To investigate whether the mPFC contributes to generating reward pre...
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Drug-related behaviors in both humans and rodents are commonly thought to arise from aberrant learning processes. Preclinical studies demonstrate that the acquisition and expression of many drug-dependent behaviors involves the ventral tegmental area (VTA), a midbrain structure comprised of dopamine, GABA, and glutamate neurons. Drug experience alters the excitatory and inhibitory synaptic inpu...
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Multiple Personalities in the Ventral Tegmental Area
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Background: Nicotine can activate dopaminergic neurons within the ventral tegmental area (VTA). However, there is no evidence about complete inhibition of VTA on nicotine reinforcement. Methods: in the present study, we used conditioned-place preference (CPP) method to study the effect of transient inhibition of left and/or right side of the VTA by lidocaine on nicotine reward properties. Male ...
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ژورنال
عنوان ژورنال: Behavioural Brain Research
سال: 2009
ISSN: 0166-4328
DOI: 10.1016/j.bbr.2009.05.008